I wanted to have gimp on my mac. As it was suggested on the Wilber loves apple site, I also installed XQuartz - X11.app improved comparing to version shipped with leopard. It works fine. With this little hack I was even able to get rid of the most annoying feature of some X11 apps running on Mac. :)
While browsing WLA forum I found information, that there is native OS X gtk port which allows to build almost fully useable gimp - very interesting.
Unfortunately after X11.app upgrade OpenOffice stopped working. :( It is still possible to run it with console, but not from the icon. Looking for the solution I found more interesting OS X resources: